Magnesium Malate has Health Benefits.
Magnesium offers many health benefits. It is an anti-inflammatory and can fight depression. Although magnesium is difficult to absorb, it is easier to absorb when it is bound to a salt.
One such salt formulation is magnesium malate. This is a mixture of magnesium and malic acid. It can be found in apples. This magnesium formulation may benefit those suffering from over-excitation of neuromuscular systems, such as chronic fatigue syndrome or Fibromyalgia. Magnesium and malic acids often recommend these conditions, though early research has not shown a benefit.
Magnesium is important in developing cells and maintaining muscles, bones and nerves. A 2016 review showed that magnesium levels in foods have declined in many industrialized countries. People who suffer from a magnesium deficiency might be unable to correct it by diet alone.
Malic acid can also be used alone, as you may have heard. People who want to increase muscle performance, decrease fatigue after exercise, and improve their mental focus often take it alone.
Health Benefits
Magnesium is found in many forms and regulates many important functions and systems within your body.
- Nerves, including neuroexcitability
- Muscles
- Blood sugar levels
- Blood pressure
- Production of protein, bones, and DNA
Many of these factors are considered dysregulated in chronic fatigue syndrome and Fibromyalgia.
Although not many studies have been done with the magnesium malate formulation, there is evidence that it can be used for various purposes.
Salt formulations that combine magnesium with different chemicals have different intestinal absorption rates. Other than magnesium malate, there are other options.
- Magnesium sulfate
- Magnesium oxalate
- Magnesium citrate
Studies on animals indicate magnesium malate might have a higher bioavailability than the other forms. One salt combination might be able to have its effects on another if it contains enough magnesium. The lower-end threshold dose for one salt combination cannot be used with another. This is an important point to remember when you interpret this research.
Neuromuscular Excitability
Magnesium’s effects on hypertension, neuronal excitation and other conditions may help with neuromuscular excitability. These conditions include:
- According to a Review, many case studies show the promise of oral magnesium to alleviate bruxism(jaw clenching and teeth-gnashing), which is a common condition in people who take stimulant medication.
- Restless legs syndrome (RLS). A study on 100 people with type 2 diabetes showed that oral magnesium supplementation significantly improved RLS symptoms. RLS is characterized by an insatiable urge to move the legs.
- Postpartum seizures According to a 2011 Review, among 1,687 women having seizures after pregnancy, those who were given intravenous magnesium salt showed a 52 per cent lower chance of convulsions in the future than those who were given diazepam.
Preeclampsia can be caused by magnesium deficiency during pregnancy. This can also hinder fetal development. The magnesium requirements of pregnant mothers can rise to 400 mg (mg) to repair and maintain their body’s tissues. Supplements can be used to meet this need, and they are safe for the baby.
Fibromyalgia, Chronic Fatigue Syndrome
The 2010 review on treatments for fibromyalgia/chronic fatigue syndrome found that magnesium malate was one of the best supplements for managing these symptoms.
Malic acid and magnesium help to produce energy for your cells in Adenosine Triphosphate (ATP). Numerous studies have shown that ATP is deficient in patients with fibromyalgia or chronic fatigue syndrome.
A 2016 study published by the journal Pain Management suggests that low magnesium and zinc levels in fibromyalgia patients could encourage a process known as excitotoxicity. In this, the neurotransmitter glucose is overstimulated and carried away.
A 2015 feasibility study suggested that magnesium malate supplementation may increase energy and relieve pain in patients with Fibromyalgia.
A 2019 review of the literature found that magnesium and malic acids had little to no effect on fibromyalgia pain and depression.
